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Lactobacillus reuteri (Firmicutes) led to reduced brain and serum GABA, downregulation of GABA-A receptors, and diminished 5-HT and DA, neurochemical changes that coincided with anxiety- and depression-like behaviors (Li N
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20,189 Copper chelators have also been shown to enhance the effectiveness of immune cells such as CD8 + T cells and natural killer (NK) cells in the tumor microenvironment (TME), thereby slowing tumor growth and improving survival rates in mice
This hypothesis remains to be tested empirically
