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Stitziel NO, Khera AV, Wang X, Bierhals AJ, Vourakis AC, Sperry AE, et al

Yu D, Shu XO, Rivera ES, et al

Although generally benign, there has been a rare case reported where a benign macule progressed into malignant melanoma.[2] This creates a challenge in distinguishing between these lesions clinically

Gynecologists are particularly wary of pigmented lesions of the vulva because the prognosis for vulvar melanoma is poor due to the tendency for increased tumor thickness at the time of presentation
