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These projections assume consistent daily dosing at 300-500 mcg subcutaneous, caloric deficit of 300-500 calories per day, and regular physical activity
[2] [11] As of 2026, retatrutide has not received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA), and it remains an experimental compound available only within authorised clinical trial settings
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After that, they are given once a month to keep levels up
