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For example, a mutation in the catalytic domain of Nox2 or in the domain responsible for interacting with the other NADPH subunits leads to a total loss of oxidative burst, whereas some mutations in the dehydrogenase domain have no effect on ROS production by phagocytes (Holland, 2013
DS5 Hydratase, a C-10 Positional- and Cis Unsaturation-Specific Enzyme
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Once outside the cell, GSH is cleaved into Cys-Gly by the enzyme -glutamyl transpeptidase (-GT), which is located on the astrocytic cell membrane
