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In diabetes, elevated IL-6 exacerbates oxidative stress by upregulating NADPH oxidase activity and ROS production, particularly in adipose and muscle tissues, contributing to systemic inflammation and insulin resistance [30]

A human-like glutaminase-free asparaginase is highly efficacious in asns(Low) leukemia and solid cancer mouse xenograft models

doi: 10.2147/IJN.S406627 249 WangYWangWGuRChenJChenQLinTet al
