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In particular, the iodothyronine deiodinases (DIO) and glutathione peroxidases (GPX1) play an essential role in thyroid physiology and safeguard against diseases caused by immunological dysregulation and oxidative stress (OS) [6]
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These properties make them attractive biomolecules for the design of low molecular weight metallo-complexes with ROS-scavenging properties under pathological conditions

doi: 10.1177/0300060518768969
