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Future research should focus on developing more robust, multiscale modeling strategies that bridge in vitro findings with in vivo outcomes, while also leveraging artificial intelligence and machine learning to enhance predictive accuracy and accelerate the clinical translation of innovative DDS

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The mixture was subsequently centrifuged (13,000 rpm, 4 C, 20 min), and the obtained supernatants were filtered through a 0.22 m microfiltration membrane and added to an injection vial for a UPLC-MS analysis
