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Collectively, these findings suggest that extracellular metabolome profiling is a robust approach to revealing T cell metabolic characteristics in vitro

Mitochondrial import and -oxidation of palmitate is important for VACV replication since treatment of infected cells with etomoxir, an inhibitor of mitochondrial import of long-chain fatty acids, and trimetazidine, an inhibitor of -oxidation, both reduce viral yield compared to DMSO-treated cells