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This measurement was used to investigate the efficacy of using 1/10 of the MIC of PZA and INH in controlling M

Although in most cases the disease can be resolved on its own, in severe cases patients may not resist the diffuse and massive alveolar damage associated with disease progression and, ultimately, pass away

Furthermore, NINJ1 appears to play a role in the later stages of ferroptotic cell death processes (cell lysis/LDH release) [33] and is dispensable for initial steps such as lipid peroxidation, channel-mediated calcium influx, and cell swelling [35]

Hence, the intracellular redox state, which is characterized by the levels and ratios of oxidized (GSSG) and reduced (GSH) glutathione, is regarded as a significant indication of the cellular health (Lu 2013)