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This difference in succinate levels between seals and humans experiencing hypoxia is consistent with the human cells, but not the seal cells, needing to rely on glycolysis during hypoxia, as seals may use succinate as their energetic substrate instead

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Conclusions In conclusion, we suggest that Dihexa rescues cognitive impairment and recovers memory by ameliorating neuronal loss and inhibiting inflammation and glial activation via PI3K/AKT signaling pathways in APP/PS1 mice

Both CA I and CA II are integral members of the broader carbonic anhydrase family, responsible for catalysing the interconversion of carbon dioxide and water to bicarbonate and protons 94