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However, alignment analysis also demonstrated the presence of a considerable degree of conserved residues in the main sites of enzyme (Supplementary Figure S5)

doi: 10.1161/01.atv.13.4.590

& Lambert, J
Translational limitations: bioavailability, effective dose and delivery Although preclinical data is encouraging, there are a number of translational challenges limiting the clinical application of phytochemical-induced ERK modulation
