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In this study, mice that went gray did not return to their original color when stress was no longer a factor
in other words, it is only efficacious if it is also bioavailable, the researchers wrote

Administration of the Nrf2-ARE activators sulforaphane and carnosic acid attenuates 4-hydroxy-2-nonenal-induced mitochondrial dysfunction ex vivo

Each one is a clear yes/no question tied to a real-world outcome
