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It said its consultations encouraged shared decision-making, where individuals are given balanced information on potential mechanisms, theoretical benefits and uncertainties
However, this difference in flux was primarily due to nutrient composition differences between plasma and cell culture medium, with supraphysiological glucose concentrations and a lack of appropriate TCA cycle fuels (e.g., lactate, shared metabolic demand that prioritizes rapid biosynthesis over efficient energyketone bodies, amino acids) in the latter (10, 11)

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