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Cardiac energy metabolism in heart failure

Therefore, cancer cells not only use FAO to oxidize fatty acids and to derive energy by mitochondria but they also use acetyl-CoA to endogenously synthesize fatty acids in the cytosol using NADPH as key cofactor for anabolic enzymes (Koundouros and Poulogiannis, 2020)
Mitochondria are the major source of reactive oxygen species (ROS) in cells
