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Targeting CD47 for cancer immunotherapy

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Consistent use is important

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Sirtuins are a family of NAD + -dependent deacylases that have been shown to regulate a myriad of biological functions, ranging from cell growth to lifespan extension, including oxidative stress, DNA damage, glycolysis, gluconeogenesis, and lipogenesis [1316]

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This is consistent with the phase 2b clinical trial, where the total 12-week result was 2.8kg (6.2 lbs) additional fat loss versus placebo (clinical trial data)

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