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Description
Vitamin B6-dependent epilepsy is a group of autosomal recessive disorders caused by mutations in the genes for phosphatidylinositol binding protein (PLPBP), acetaldehyde dehydrogenase 4 family member A1 (ALDH4A1), acetaldehyde dehydrogenase 7 family member A1 (ALDH7A1), pyridoxal (amine) 5'-phosphate oxidase (PNPO), and tissue non-specific alkaline phosphatase (TNSALP)
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It is the very activity that affects chromosomal end maintenance in laboratory models
This also means the counteracted oxidative stress was as a result of the lysis of endothelial cells (Vukojevic et al., 2018)
