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The researchers used Annexin-V FACS analysis and DNA laddering to demonstrate that Sag activated apoptosis in the sensitive cell lines in a dose- and time-dependent manner
[DOI] [PubMed] [Google Scholar] Roberts B
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Going forward, tailoring iron-based therapies to each diseases specific iron dysregulation profile and combining iron modulation with other neuroprotective strategies will likely be crucial for therapeutic success
