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The future clinical translation of such multiplexed imaging biomarkers will be critical for intelligent patient stratification, monitoring early molecular response, and detecting emergent resistance mechanisms, thereby guiding adaptive therapy within this novel framework

This browning is mediated through multiple pathways including SIRT1/PGC-1 activation, increased expression of thermogenic genes (UCP1, PRDM16, PPAR), and enhanced mitochondrial biogenesis

The amygdala and the relevance detection theory of autism: an evolutionary perspective

4.5 Redox Balance Glutamine plays a crucial role in maintaining cellular redox homeostasis by supporting the synthesis of glutathione (GSH), one of the major antioxidants in the cell