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By interfering with the metabolic pathways involved in polysaccharide synthesis, baicalin hampers the accumulation of these carbohydrates, leading to a destabilized biofilm structure
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Additionally, GSK-J4, a dual inhibitor of histone lysine demethylase 6A/6B that prevents H3K27 demethylation, can suppress palmitic acid (PA)-induced hypersensitivity to ferroptosis by inhibiting ACSL4 expression and lipid peroxidation in cardiomyocytes[204]
