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The biocomplexity of glioma cells, including their heterogeneity, high proliferation rate and infiltration, contributes to their high recurrence and drug resistance
Unlike antioxidants reliant on dietary intake, GSH is produced internally, making it a cornerstone of the bodys defense system

& Navari-Izzo, F

Because of this instability, most NAD supplements are precursors like nicotinamide riboside (NR) instead of active NAD+ itself
