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doi: 10.1016/j.cell.2024.03.011
The same study also demonstrated that perturbing glutamine pathway either via glutamine depletion or by using specific chemical inhibitors or due to genetic polymorphism (e.g., GLS2, SLC7A5, and SLC1A5), decreased T-cell associated cytokine production by the macrophages (PMID: 30541099)
doi: 10.1023/a:1011136724577 29 EggersS.BarkerA
They are mainly lipophilic anionic transporters and are reported to transport free or conjugates of glutathione (GSH), glucuronate, or sulphate
