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Most therapeutic peptides degrade within minutes in stomach acid and pancreatic proteases, which is why oral peptide drug delivery is dominated by formulation engineering (enteric coatings, absorption enhancers, prodrug conjugates)

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The evidence is unambiguous: seven-day dihexa protocols produce cognitive improvements measurable 30+ days post-treatment despite complete plasma clearance within 12 hours of the final dose

investigators considered them unrelated, but no long-term oncology safety data exists)
