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[129] reported that treatment of multiple sclerosis (MS) patients with ALCAR for 6 months resulted in decreased levels of reactive nitrogen species and protein nitration in CSF, and increased GSH levels and GSH/GSSG ratio compared to untreated MS subjects or patients with noninflammatory neurological conditions

In general, reporting of randomization methods and treatment allocation was clearly stated in De Grandis and colleagues 25 and in Youle and colleagues 28 whereas it was uncertain in Sima and colleagues 24 therefore associated with an uncertain bias risk

Acetyl-L-carnitine improves pain, nerve regeneration, and vibratory perception in patients with chronic diabetic neuropathy: An analysis of two randomized, placebo-controlled trials

Nutrients 12, 952