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These mechanisms together may explain why B12 has been studied in conditions such as diabetic neuropathy, nerve injury, and radicular pain syndromes similar to sciatica

[41] investigated the effect of other two exogenous osmoprotectants (proline and trehalose) on a salt-sensitive rice variety, where salt stress resulted in growth reduction, increase in the Na + /K + ratio, increase in proline level and up-regulation of proline synthesis genes (pyrroline-5-carboxylatesynthetase, P5CS
