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They form in areas like the bladder, pelvis and renal cortex, leading to abdominal pain, nausea, vomiting and painful urination
Results: Neuron-specific gene ablation of prolyl-4-hydroxylase domain 2 (PHD2) protein, negatively regulating the protein stability of HIF- in an oxygen dependent manner, reduced brain injury and functional impairment of mice after acute stroke in a HIF-dependent manner

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Liu T, Zhang L, Joo D, Sun SC
