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We established the optimal NaBt concentration for PC12-ND6 cells (5 mM) and E17.5 hippocampal neurons (2 mM) to induce maximal acetylation levels with minimal cellular toxicity, and showed that NaBt preferentially acetylated the lysine residues of the histone H3 at positions 9 and 27 (Fig

Yes, our LC-MS/MS platform quantifies key niacin metabolites including NAD, NADP, and their reduced forms (NADH, NADPH), which are essential for energy metabolism and redox balance, providing researchers with deeper insights into cellular health, metabolic pathways, and therapeutic strategy development

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