glutathione esters toxicity Role of in Cancer: From Mechanisms to Therapies Our Science – Nacuity Pharmaceuticals

Indeed, a pilot study on young patients with ALL suffering from chemo-induced liver toxicity found that treatment with milk thistle led to a "trend towards significant reductions in liver toxicity."24 The researchers state that future studies are needed to zero in on the ideal dosage and duration of treatment, but their findings suggest that milk thistle may be a promising intervention for acute liver injury secondary to chemo

But heres where people get confused

Gauter-Fleckenstein, B

The reduction of GSSG by glutathione reductase (GR) to form GSH depends on the supply of the reductant nicotinamide adenine dinucleotide phosphate, which is provided by the pentose phosphate shunt[40]