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Review Date: 24 Jan 2020 | Promega Corp

Second generation corticosteroids Beclomethasone diproprionate and slow release budesonide are second generation corticosteroids with a high affinity for the intracellular glucocorticoid receptor in the GI tract, exerting local and selective, potent anti-inflammatory effects at the site of inflammation[33]

These results suggest that while the electrophysiological improvement observed could not be related to the rescue of the insulin levels in the Casp1 / diabetic mice, we cannot exclude that insulin could be also involved in the electrophysiological improvement observed in Nlrp3 / diabetic mice

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