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The expression of lncRNA SEMA5A-IT1 in serum small circulating extracellular vesicles of patients after CPB is higher than that before CPB, which is inversely proportional to the level of creatine kinase-MB

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They determine a better dispersion and increased solubility

The phenotype of the proband was less severe than other IGF1 mutation patients with normal birth size (3.0kg) but significant post-natal growth impairment (presenting height -4.0 SD), normal hearing, normal development except for attention deficit hyperactivity disorder and mildly reduced serum concentrations of IGF-I (-2.2 SD) with normal IGFBP-3 serum levels (-1.25 SD)