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Chemotherapy is among the most common techniques for treating lung cancer
Five years later (in 2008), the importance of ferrous iron, the system xc - (xCT) controlled cystine/cysteine redox cycle, and the glutathione peroxidase 4 (GPX4)-glutathione (GSH) redox system in lipid peroxidation and non-apoptotic cell death was highlighted by different research groups[10-12]
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This observation contrasts with a previous study on pckA mutant, wherein elevated cytosolic ATP levels increased drug tolerance when grown in acetate medium 41
