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Therapy and Prognosis Revised treatment standards over the last years have significantly improved outcome and prognosis (21)

Email: [email protected] Received: 07 Feburary 2023 / Revised: 02 March 2023 / Accepted: 22 March 2023 / Published: 29 March 2023 DOI: 10.31491/APT.2023.03.109 Abstract Sleep deprivation is known to cause memory impairment and is associated with inflammation and cell damage linked to neurodegenerative diseases

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The open 2:2 architecture observed here therefore likely represents the minimal fully active LepR signaling complex, and the functional role of the symmetric 3:3 assembly remains to be determined