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Hughes et al
Feilchenfeld Z, Ycel YH, Gupta N (2008) Oxidative injury to blood vessels and glia of the pre-laminar optic nerve head in human glaucoma

Findings of NAD and glutathione changes are reported in genetic metabolic diseases as well as in degenerative, age-related diseases 1,2

These metrics not only quantify disease burden but also provide prognostic information, as demonstrated by the substantially worse outcomes observed in patients with advanced functional limitations