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Description
In a randomized placebo-controlled trial, metformin treatment was associated with a mean decrease in vitamin B 12 concentration by 19% and an increase in homocysteine concentration by 5% [52]

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It has been examined in laboratory and clinical research models related to metabolic regulation , energy balance , and feeding behavior

Without proper guidance from a medical professional, it is possible to ingest excessive amounts of B12 especially if you misread the label or mistake micrograms for milligrams, for instance
