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PCA score plots showed a significant separation trend of metabolites for the pure culture of S

Decreased insulin shifts the balance between protein synthesis and protein degradation toward degradation, resulting in a net loss of protein

Furthermore, studies on serum from SZ patients showed elevated levels of polyamine oxidase (the enzyme responsible for degrading PAs) (96, 97), while the activities of three enzymes involved in PA synthesisornithine aminotransferase, antizyme inhibitor 1 (AZIN1), and ornithine cyclodeaminase were found to be reduced in the prefrontal cortex of both treated and untreated patients (98), ultimately potentially leading to disrupted polyamine homeostasis

69 Conditions associated with subnormal ALP levels Reported causes subnormal levels of ALP include ALP mutations, Wilsons disease, malnutrition, magnesium deficiency, zinc deficiency, and a protein-free diet