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Description
Maria G

In addition, an FSP1-dependent noncanonical VK cycle has recently been reported to function as a ferroptosis suppressor, and FSP1 efficiently reduced VK to its hydroquinone VKH 2 form, which function as a potent radical-trapping antioxidant to inhibit lipid peroxidation[18]

they minimize programmed cell death by hindering phosphorylation of the ERK/JNK pathway, blocking transcription and translation of apoptosis-related proteins like caspase-3 and Bax, while also elevating levels of Bcl-2 factor, and maintaining mitochondrial membrane potential stability

This protects against atherosclerosis, insulin resistance, obesity, and type 2 diabetes [109]
