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Despite their diverse etiologies, these diseases converge on several recurring pathological themes, including oxidative stress, chronic inflammation, hormonal imbalance, aberrant extracellular matrix deposition, and dysregulated cell survival

428 On another hand, mitophagy could maintain the balance of oxidation and antioxidation through dynamically removing damaged mitochondria, thus avoiding excessive ROS accumulation and oxidative stress

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

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