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Furthermore, dual-luciferase assays were employed to illuminate the interaction of miR-146a-3p with AQP4 mRNA

The study showed that the NOAEL of rotigotine behenate-loaded PLGA was at 360 mg/kg, supporting its safety and potential for clinical translation 138

A single IV session raises blood levels for 24 to 72 hours, then levels return toward baseline

Polymeric nanoparticle platforms have been explored for a wide range of medical applications, including targeted cancer therapy, gene delivery, and immunization against infectious diseases such as malaria, HIV, COVID-19, and tuberculosis [119]
