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The argument made by some vendors was that because PDA uses an arginine counterion rather than acetate, it constitutes a distinct chemical entity not covered by the BPC-157 Category 2 ruling

It is pointed out that hydrogels can prolong the residence time of drugs in the eye and control drug release, thus improving the bioavailability of drugs (Han et al., 2024)

FDA to Revisit BPC-157 and Other Peptides On July 2324, 2026, FDA's Pharmacy Compounding Advisory Committee will consider whether BPC-157, along with KPV, TB-500, MOTS-c, Semax, Epitalon, and Emideltide, should be included on the Section 503A Bulks List for pharmacy compounding

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