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This indicates a strong need for better understanding of the tumor response to the treatment to overcome treatment resistance and reduce tumor progression, as well as to identify therapeutic selectivity, increasing the treatment sensitivity of the tumor while reducing adverse effects in normal tissue [1]

The reattachment fibers from the ends of the muscle could be traced into the new bone formed at the surface (note, on day 3 post-detachment, there was an increase in mesenchymal cells with periosteum reactivation)

10.1126/science.1167852 251 SchwenkM.DutziI.EnglertS.MicolW.NajafiB.MohlerJ.et al

Advances in therapy , 36 , 47-58
