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Animal models are valuable for identifying mechanisms and generating hypotheses, but they do not always translate directly to human outcomes

[10] Subcutaneous injections are relatively quick (done in a few minutes) and can be administered in a doctors office or self-administered at home if the patient is comfortable with it

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These alterations promote systemic low-grade inflammation through an imbalance between elevated pro-inflammatory cytokines (e.g., IL-6, TNF-) and anti-inflammatory mediators (e.g., IL-10) (267269)