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Despite compensatory upregulation of sodium-dependent citrate transporters (NaCitT) in advanced tumors, accelerated citrate consumption consistently outpaces extracellular uptake (75)

As of 2025, no large-scale human RCTs on BPC-157 for musculoskeletal repair had been published

High GLS expression in colorectal cancer has been demonstrated to result in reduced T-cell infiltration and toxicity, which is a significant factor contributing to the poor prognosis observed in patients with this condition

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