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Effects of Anesthesia on Postoperative Recurrence and Metastasis of Malignant Tumors

Glutamine is a preferred fuel for both lymphocytes [11,12] and gastrointestinal (GI) tract [1], thus it plays an important role in helping to defend against infections and to assist mucosa in being a barrier against infection (Figure 1)

Among HDAC family members, SIRT1 catalyzes the deacetylation of lysine 28 on Tau, inhibiting its normal function and facilitating aggregation (132)

The enzyme that acts as the rate-limiting step in cholesterol biosynthesis is 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase [74,75,76,77,78,79,80]