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6-phosphogluconate dehydrogenase (6PGD) converts 6-PG to ribulose 5-phosphate (Ru5P) and generates NAPDH (Figure 1)

doi: 10.1038/nri.2016.42 210 WangLde ZoetenEFGreeneMIHancockWW
Furthermore, EODF reduced MPTP-induced striatal dopamine depletion, increased phosphorylation of PI3K and Akt, and increased phosphorylation of ERK and CREB, further supporting the involvement of neurotrophic factors in the observed neuroprotection

The Oxidative Burst: Ozone acts as a potent biological modifier , training your body to handle oxidative stress more efficiently
