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Sustained PI3KAktmTOR pathway activation caused by persistent stimulation with beads or IL2 or tonic signaling leads to terminal differentiation of CAR-T cells and impairs antitumor immunity
Highly purified eicosapentaenoic acid treatment improves nonalcoholic steatohepatitis
Glutamine catabolism promotes the synthesis of glutathione, thus influencing T cell differentiation [31]
300 Stress responses mediated by SOS and sigma factor RpoS The SOS response is triggered by DNA damage, allowing repair of genetic material to enhance cell survival
