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Indeed, pyroptosis is a rapid and inflammatory form of lytic programmed cell death [86]
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-sitosterol binds strongly to glycogen synthase kinase-3 (GSK-3)

Hypotensive effect of aqueous saffron extract ( Crocus sativus L.) and its constituents, safranal and crocin, in normotensive and hypertensive rats

The wide fluctuations in RMSF and RMSD are indications of perturbation of the system, which may be due to conformational changes within the protein complex system and the repositioning of ligands inside the binding sites [30,34]
