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And talking to very great colleagues of yours, Bret, that work with you guys together and that work in the whole metabolic psychiatry field
ECG features favoring Mobitz I PR prolongation (implying slow conduction within the AV node)

[DOI] [PubMed] [Google Scholar] 57.Jeukendrup A.E

Therefore, we hypothesize that peripheral target engagement in SOD1 G93A mice could prove to have effects by amelioration of peripheral hypermetabolism and thereby, e.g., inflammation and oxidative stress