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b12 injection leg Shots at Home: How, Where & How Often to Inject Yourself How to Self-Inject Vitamin B12
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This would be dependent on multiple factors including resources and legal requirements

Totally harmless

Nat Rev Microbiol (2022) 20(5):27084
For hematocrit and reticulocyte counts, recommendations are to repeat these tests daily from the 5th to 7th days of treatment and then frequently until the hematocrit returns to a normal range
