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doi: 10.1080/14786419.2014.883394 [DOI] [PubMed] [Google Scholar] 139.Chien HJ, Hu HM, Tsai SJ, et al

Yes, hormonal changes, such as during pregnancy or due to medications, can increase melanin production

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Therapeutic efficacy of topically applied antioxidant medicinal plant extracts in a mouse model of experimental dry eye
