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Lipid nanoparticles enabling gene therapies: from concepts to clinical utility

The targeted delivery of gas donors and the controlled release of reactive gas are achieved through the structural design and functional optimization of gas delivery metallic nanomaterials, which are regulated by multiple exogenous or endogenous stimuli

Eine hhere (10 g/kg) Dosis war entweder nach einem einzigen oder tglichen Regime wirksam, wohingegen eine niedrigere (10 ng/kg) Dosis, die bisher als Einzelanwendung unwirksam verabreicht wird, bei Anwendung in einem tglichen Regime wirksam wurde

Furthermore, introducing scavengers (PTIO for NO and HT for H 2 S) and inhibitors (L-NAME for NO and PAG for H 2 S) reversed the positive effects of H 2 S and NO, exacerbating damages under Ni-induced stress