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A cluster of amyotrophic lateral sclerosis in New Hampshire: a possible role for toxic cyanobacteria blooms

The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading

( Figure 3

Research suggests it acts through modulation of several interconnected signaling pathways simultaneously a broad mechanism of action that helps explain its observed multisystemic effects in laboratory models, and that also makes it challenging to evaluate through conventional single-target drug development frameworks
